Transforming growth factor-β1 and lung allograft fibrosis1
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چکیده
منابع مشابه
Transforming growth factor-β1 and diabetic nephropathy.
Transforming growth factor-β1 (TGF-β1) is established to be involved in the pathogenesis of diabetic nephropathy. The diabetic milieu enhances oxidative stress and induces the expression of TGF-β1. TGF-β1 promotes cell hypertrophy and extracellular matrix accumulation in the mesangium, which decreases glomerular filtration rate and leads to chronic renal failure. Recently, TGF-β1 has been demon...
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INTRODUCTION Morphea (localized scleroderma) is a rare cutaneous disease characterized by skin fibrosis of unknown pathogenesis. Transforming growth factor-β (TGF-β) is a potent profibrotic factor. The role of TGF-β in morphea remains unclear. AIM The goal of this study was to estimate the expression level of TGF-β1 in skin and peripheral blood mononuclear cells as well as the plasma levels o...
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ژورنال
عنوان ژورنال: European Journal of Cardio-Thoracic Surgery
سال: 1998
ISSN: 1873-734X,1010-7940
DOI: 10.1016/s1010-7940(98)00048-7